Funding Opportunities
National Cancer Institute Banner U.S.National Institutes of Health National Cancer Institute
Skip navigation links
Funded Research
Funding Opportunities
Grant and Policy Information
Research Resources
News and Reports
About Us
Funding Opportunites Banner
DCB - Participating Program Announcements (PAs, PARs, PAS), Requests for Applications (RFAs), and NIH Guide Notices
DCB - Applications to Promote Research Collaboration (DCB-APRC) Program

An opportunity for current DCB grantees to seek supplemental funding for existing DCB-funded research projects to support and encourage multidisciplinary scientific collaboration among DCB and NCI grantees, as well as with other members of the scientific community. This initiative known as the Division of Cancer Biology Activities to Promote Research Collaborations (DCB-APRC) Program can support novel collaborative activities in cancer biology that bring together new ideas and approaches from disparate scientific disciplines.  The proposed DCB-APRC activities must be within the overall scope of the active parent DCB grant.

Guidelines and Instruction for APRC Applicants

The NCI’s Division of Extramural Activities maintains the listing of all NCI Funding Opportunities.
The NIH Common Fund / Roadmap

The NIH Common Fund was enacted into law by Congress through the 2006 NIH Reform Act to support cross-cutting, trans-NIH programs that require participation by at least two NIH Institutes or Centers (ICs) or would otherwise benefit from strategic planning and coordination.  The Common Fund supports the series of transformative programs that were established under the NIH Roadmap for Medical Research, as well as other non-Roadmap activities.

For additional information, please visit the NIH Common Fund website

NIH Guide for Grants and Contracts

The NIH Guide for Grants and Contracts is the official publication for NIH medical and behavioral research grant policies, guidelines and funding opportunities.

NIH Guide announcements (PAs, RFAs and Notices) are published daily.  At the end of each work week (usually on Friday afternoon), NIH transmits an e-mail to the NIH Guide LISTSERV (see Subscribe/Unsubscribe instructions) with a Current Weekly Table of Contents (TOC), including links to announcements published during the week.  See the January 13, 2005 NIH Guide Notice for information on searching the NIH Guide and on Expiration Dates.  The NIH Guide is also used by NIH Contracting offices and other HHS agencies, to announce their funding opportunities.

The NIH Guide serves in lieu of the Federal Register, in compliance with the Administrative Procedures Act.  Occasionally, unofficial notices of interest to the scientific research community are published.  The NIH considers applications for the support of basic or clinical biomedical, behavioral, and bioengineering research.

For more information and query tools, please visit the NIH Guide website

General Information about Funding Opportunities

Funding Opportunity Announcement (FOA)

A publicly available document by which a Federal agency makes known its intentions to award discretionary grants or cooperative agreements, usually as a result of competition for funds. Funding opportunity announcements may be known as program announcements, requests for applications, notices of funding availability, solicitations, or other names depending on the agency and type of program. Funding opportunity announcements can be found at and in the NIH Guide for Grants and Contracts.In addition, NIH and other HHS Agencies have developed omnibus Parent Announcements for common grant mechanisms that have transitioned to electronic submission, for use by applicants who wish to submit what were formerly termed “unsolicited” or "investigator-initiated" applications.

Program Announcement (PA)

  • Identifies areas of increased priority and/or emphasis on particular funding mechanisms for a specific area of science
  • Usually accepted on standard receipt (postmarked) dates on an on-going basis
  • Remains active for three years from date of release unless the announcement indicates a specific expiration date or the NIH Institute/Center (I/C) inactivates sooner (see January 13, 2005 NIH Guide Notice for more information on Expiration Dates)
  • Special Types
    • PAR: A PA with special receipt, referral and/or review considerations, as described in the PAR announcement
    • PAS: A PA that includes specific set-aside funds as described in the PAS announcement

Request for Application (RFA)

  • Identifies a more narrowly defined area for which one or more NIH institutes have set aside funds for awarding grants
  • Usually has a single receipt (received on or before) date specified in the RFA announcement
  • Usually reviewed by a Scientific Review Group convened by the issuing awarding component

Notice (NOT)

  • Announces policy and procedures, changes to RFA or PA announcements, RFPs and other general information items
  • Inquiries about specific Notices, PAs, and RFAs published in the NIH Guide, should be directed to the NIH staff member(s) identified in each announcement.

Numbering System

  • PA Numbering (e.g. PA-10-008): Indicates a PA issued in 2010 or for funding in 2010 (10) with an associated serial number (008).
  • RFA Numbering (e.g. RFA-CA-10-004): Indicates an RFA issued by NCI (CA) in 2010 or for funding in 2010 (10) with an associated serial number (004).
  • Notice Numbering (e.g. NOT-OD-10-025): Indicates a Notice issued by the NIH Office of the Director (OD) in Fiscal Year 2010 (10) with an associated serial number (025).